Optimization of Novel Naproxen-Loaded Chitosan/Carrageenan Nanocarrier-Based Gel for Topical Delivery: Ex Vivo, Histopathological, and In Vivo Evaluation

• Main Authors: Sobia Noreen (Author), Fahad Pervaiz (Author), Akram Ashames (Author), Manal Buabeid (Author), Khairi Fahelelbom (Author), Hina Shoukat (Author), Irsah Maqbool (Author), Ghulam Murtaza (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Naproxen (NAP) is commonly used for pain, inflammation, and stiffness associated with arthritis. However, systemic administration is linked with several gastrointestinal tract (GIT) side effects. The present work aims to prepare and evaluate NAP nanoparticulate shells of chitosan (CS) and carrageena...