Targeting the non-structural protein 1 from dengue virus to a dendritic cell population confers protective immunity to lethal virus challenge.

• Main Authors: Hugo R Henriques (Author), Eline V Rampazo (Author), Antonio J S Gonçalves (Author), Elaine C M Vicentin (Author), Jaime H Amorim (Author), Raquel H Panatieri (Author), Kelly N S Amorim (Author), Marcio M Yamamoto (Author), Luís C S Ferreira (Author), Ada M B Alves (Author), Silvia B Boscardin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue is the most prevalent arboviral infection, affecting millions of people every year. Attempts to control such infection are being made, and the development of a vaccine is a World Health Organization priority. Among the proteins being tested as vaccine candidates in preclinical settings is the...