Expression of CYLD and NF-κB in Human Cholesteatoma Epithelium

• Main Authors: Jae Yong Byun (Author), Tae Young Yune (Author), Jee Youn Lee (Author), Seung Geun Yeo (Author), Moon Suh Park (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The tumor suppressor CYLD is a deubiquitinating enzyme that inhibits activation of the NF-κB, which has key roles in inflammation and apoptosis. We hypothesized that CYLD may regulate the NF-κB signaling pathway in cholesteatoma. We conducted immunohistochemistry to examine the expression of CYLD an...