Characteristics of Gabexate Mesilate-Induced Cell Injury in Porcine Aorta Endothelial Cells

• প্রধান লেখক: Tomoko Aki (লেখক), Nobuaki Egashira (লেখক), Mika Hama (লেখক), Yui Yamauchi (লেখক), Takahisa Yano (লেখক), Yoshinori Itoh (লেখক), Ryozo Oishi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2008-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Gabexate mesilate (GM), a serine protease inhibitor, often causes severe vascular injury, when injected in high concentration. In the present study, we investigated the mechanisms for the cytotoxicity of GM on porcine aorta endothelial cells (PAECs). GM (0.5 -5.0 mM) decreased cell viability in a do...