Trichomicin Suppresses Colorectal Cancer via Comprehensive Regulation of IL-6 and TNFα in Tumor Cells, TAMs, and CAFs

• Main Authors: Xi Zhao (Author), Xiaoqiang Qi (Author), Wenrui Lian (Author), Xin Tong (Author), Hua Wang (Author), Liya Su (Author), Ping Wei (Author), Zhuochen Zhuang (Author), Jianhua Gong (Author), Liping Bai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trichomicin, a small-molecule compound isolated from fungi, has been identified with bioactivity of antitumor. In this study, a colon cancer subcutaneous mice model was used to evaluate the antitumor effects of Trichomicin in vivo. Treatment with Trichomicin significantly inhibited tumor growth in a...