Polyunsaturated fatty acid-based targeted nanotherapeutics to enhance the therapeutic efficacy of docetaxel

• Main Authors: Thiruganesh Ramasamy (Author), Pasupathi Sundaramoorthy (Author), Hima Bindu Ruttala (Author), Yongjoo Choi (Author), Woo Hyun Shin (Author), Jee-Heon Jeong (Author), Sae Kwang Ku (Author), Han-Gon Choi (Author), Hwan Mook Kim (Author), Chul Soon Yong (Author), Jong Oh Kim (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since breast cancer is one of the most lethal malignancies, targeted strategies are urgently needed. In this study, we report the enhanced therapeutic efficacy of docetaxel (DTX) when combined with polyunsaturated fatty acids (PUFA) for effective treatment of multi-resistant breast cancers. Folic ac...