A new cellular model to follow Friedreich's ataxia development in a time-resolved way

• Main Authors: Tommaso Vannocci (Author), Nathalie Faggianelli (Author), Silvia Zaccagnino (Author), Ilaria della Rosa (Author), Salvatore Adinolfi (Author), Annalisa Pastore (Author)
• Format: Book
• Published: The Company of Biologists, 2015-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Friedreich's ataxia (FRDA) is a recessive autosomal ataxia caused by reduced levels of frataxin (FXN), an essential mitochondrial protein that is highly conserved from bacteria to primates. The exact role of frataxin and its primary function remain unclear although this information would be ver...