Exploratory Longitudinal Analysis of the Circulating CHIT1 Activity in Pediatric Patients with Obesity

• Main Authors: Ioana Țaranu (Author), Nicoleta Răcătăianu (Author), Cristina Drugan (Author), Cristina-Sorina Cătană (Author), Andreea-Manuela Mirea (Author), Diana Miclea (Author), Sorana D. Bolboacă (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophage activation and cytokine release play a pivotal role in inflammation-mediated metabolic disturbances in obesity. The proinflammatory macrophage secretes human chitotriosidase (CHIT1). The expression of the CHIT1 in visceral adipose tissue is associated with cytokine production. Our study a...