A whole‐body circulatory neutrophil model with application to predicting clinical neutropenia from in vitro studies
Abstract A circulatory model of granulopoiesis and its regulation is presented that includes neutrophil trafficking in the lungs, liver, spleen, bone marrow, lymph nodes, and blood. In each organ, neutrophils undergo transendothelial migration from vascular to interstitial space, clearance due to ap...
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Main Authors: | Wenbo Chen (Author), Britton Boras (Author), Tae Sung (Author), Wenyue Hu (Author), Mary E. Spilker (Author), David Z. D'Argenio (Author) |
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Format: | Book |
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Wiley,
2021-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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