Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis

• Main Authors: Xuan Chen (Author), Jinge Dou (Author), Zhuohui Fu (Author), Yang Qiu (Author), Ling Zou (Author), Dingming Huang (Author), Xuelian Tan (Author)
• Format: Book
• Published: University of São Paulo, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective: To investigate the involvement of IL-6/STAT3 signaling pathway activation in macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated by Porphyromonas gingivalis. Methodology: Macrophage polarization, IL-6/STAT3 expression, and the presence of...