Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis

• Autores principales: Xuan Chen (Autor), Jinge Dou (Autor), Zhuohui Fu (Autor), Yang Qiu (Autor), Ling Zou (Autor), Dingming Huang (Autor), Xuelian Tan (Autor)
• Formato: Libro
• Publicado: University of São Paulo, 2022-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Objective: To investigate the involvement of IL-6/STAT3 signaling pathway activation in macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated by Porphyromonas gingivalis. Methodology: Macrophage polarization, IL-6/STAT3 expression, and the presence of...