Development of Self-Associating SN-38-Conjugated Poly(ethylene oxide)-Poly(ester) Micelles for Colorectal Cancer Therapy

The clinical use of 7-ethyl-10-hydroxy-camptothecin (SN-38), which is the active metabolite of irinotecan, has been hampered because of its practical water-insolubility. In this study, we successfully synthesized two self-associating SN-38-polymer drug conjugates to improve the water-solubility of S...

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Bibliographic Details
Main Authors: Sams M. A. Sadat (Author), Mohammad Reza Vakili (Author), Igor M. Paiva (Author), Michael Weinfeld (Author), Afsaneh Lavasanifar (Author)
Format: Book
Published: MDPI AG, 2020-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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