Development of Self-Associating SN-38-Conjugated Poly(ethylene oxide)-Poly(ester) Micelles for Colorectal Cancer Therapy
The clinical use of 7-ethyl-10-hydroxy-camptothecin (SN-38), which is the active metabolite of irinotecan, has been hampered because of its practical water-insolubility. In this study, we successfully synthesized two self-associating SN-38-polymer drug conjugates to improve the water-solubility of S...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2020-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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