Novel zebrafish polycystic kidney disease models reveal functions of the Hippo pathway in renal cystogenesis
The Hippo signaling pathway is a kinase cascade that plays an important role in organ size control. As the main effectors of the Hippo pathway, transcription coactivators Yap1/Wwtr1 are regulated by the upstream kinase Stk3. Recent studies in mammals have implicated the Hippo pathway in kidney devel...
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2021-11-01T00:00:00Z.
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