Development and Quality Control of a Population Pharmacokinetic Model Library for Caspofungin

• Main Authors: Nuo Xu (Author), Yufei Shi (Author), Yixue Wang (Author), Wenyao Mak (Author), Wenyu Yang (Author), Kar Weng Ng (Author), Yue Wu (Author), Zhijia Tang (Author), Qingfeng He (Author), Gangfeng Yan (Author), Xiaoqiang Xiang (Author), Xiao Zhu (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Caspofungin is an echinocandin antifungal agent commonly used as the first-line therapy for invasive candidiasis, salvage therapy for invasive aspergillosis, and empirical therapy for presumed fungal infections. Pharmacokinetic (PK) variabilities and suboptimal exposure have been reporte...