Nanoseeded Desupersaturation and Dissolution Tests for Elucidating Supersaturation Maintenance in Amorphous Solid Dispersions

• Váldodahkkit: Gulenay Guner (Dahkki), Ayesha Amjad (Dahkki), Matthew Berrios (Dahkki), Manisha Kannan (Dahkki), Ecevit Bilgili (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2023-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The impact of residual drug crystals that are formed during the production and storage of amorphous solid dispersions (ASDs) has been studied using micron-sized seed crystals in solvent-shift (desupersaturation) and dissolution tests. This study examines the impacts of the seed size loading on the s...