2-Hydroxyoleic acid-inserted liposomes as a multifunctional carrier of anticancer drugs

• Main Authors: Eun-Ji Jang (Author), Woo Rim Choi (Author), Soo-Yeon Kim (Author), Soon-Seok Hong (Author), Inmoo Rhee (Author), Sang-Jin Lee (Author), Sung Weon Choi (Author), Han-Gon Choi (Author), Soo-Jeong Lim (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Studies have shown that insertion of oleic acid into lipid bilayers can modulate the membrane properties of liposomes so as to improve their function as drug carriers. Considering that 2-hydroxyoleic acid (2OHOA), a potential antitumor agent currently undergoing clinical trials, is a derivative of o...