Destabilising microtubule polymerization regulates chondrocyte dedifferentiation and inflammation via nuclear factor kappa b and β-catenin pathway

• Main Authors: Yohan Han (Author), Young Seok Eom (Author), Fahad Hassan Shah (Author), Song Ja Kim (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of cell morphological changes in colchicine-inhibited tubulin polymerization of rabbit articular chondrocytes and their involvement in dedifferentiation were investigated. Colchicine treatment resulted in the dedifferentiation of chondrocytes, which was supported by the loss of type II coll...