Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease

• Main Authors: Preeti Lakshman Kumar (Author), Ava C. Wilson (Author), Alison Rocco (Author), Michael H. Cho (Author), Emily Wan (Author), Brian D. Hobbs (Author), George R. Washko (Author), Victor E. Ortega (Author), Stephanie A. Christenson (Author), Xingnan Li (Author), J. Michael Wells (Author), Surya P. Bhatt (Author), Dawn L. DeMeo (Author), Sharon M. Lutz (Author), Harry Rossiter (Author), Richard Casaburi (Author), Stephen I. Rennard (Author), David A. Lomas (Author), Wassim W. Labaki (Author), Ruth Tal‐Singer (Author), Russel P. Bowler (Author), Craig P. Hersh (Author), Hemant K. Tiwari (Author), Mark Dransfield (Author), Anna Thalacker‐Mercer (Author), Deborah A. Meyers (Author), Edwin K. Silverman (Author), Merry‐Lynn N. McDonald (Author), COPDGene, ECLIPSE and SPIROMICS investigators (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally. COPD patients with cachexia or weight loss have increased risk of death independent of body mass index (BMI) and lung function. We tested the hypothesis genetic variation is associated with...