Uptake in the Central Nervous System of Geraniol Oil Encapsulated in Chitosan Oleate Following Nasal and Oral Administration

• Main Authors: Maria Cristina Bonferoni (Author), Luca Ferraro (Author), Barbara Pavan (Author), Sarah Beggiato (Author), Elena Cavalieri (Author), Paolo Giunchedi (Author), Alessandro Dalpiaz (Author)
• Format: Book
• Published: MDPI AG, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pharmacological activities of geraniol include anticancer and neuroprotective properties. However, its insolubility in water easily induces separation from aqueous formulations, causing administration difficulties. Here we propose new emulsified formulations of geraniol by using the amphiphilic...