The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

• Main Authors: Lasse I. Blaabjerg (Author), Holger Grohganz (Author), Eleanor Lindenberg (Author), Korbinian Löbmann (Author), Anette Müllertz (Author), Thomas Rades (Author)
• Format: Book
• Published: MDPI AG, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The increasing number of poorly water-soluble drug candidates in pharmaceutical development is a major challenge. Enabling techniques such as amorphization of the crystalline drug can result in supersaturation with respect to the thermodynamically most stable form of the drug, thereby possibly incre...