Non-small-cell lung cancer: how to manage BRAF-mutated disease

• Main Authors: Giorgia Guaitoli (Author), Lodovica Zullo (Author), Marcello Tiseo (Author), Matthew Dankner (Author), April AN Rose (Author), Francesco Facchinetti (Author)
• Format: Book
• Published: BioExcel Publishing Ltd, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BRAF mutations are reported in about 3-5% of non-small-cell lung cancer (NSCLC), almost exclusively in adenocarcinoma histology, and are classified into three different classes. The segmentation of BRAF mutations into V600 (class 1) and non-V600 (classes 2 and 3) relies on their biological character...