Loss of melusin is a novel, neuronal NO synthase/FoxO3‐independent master switch of unloading‐induced muscle atrophy

• Main Authors: Maurizio Vitadello (Author), Matteo Sorge (Author), Elena Percivalle (Author), Elena Germinario (Author), Daniela Danieli‐Betto (Author), Emilia Turco (Author), Guido Tarone (Author), Mara Brancaccio (Author), Luisa Gorza (Author)
• Format: Book
• Published: Wiley, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Unloading/disuse induces skeletal muscle atrophy in bedridden patients and aged people, who cannot prevent it by means of exercise. Because interventions against known atrophy initiators, such as oxidative stress and neuronal NO synthase (nNOS) redistribution, are only partially...