Diisopropylphenyl-imidazole (DII): A new compound that exerts anthelmintic activity through novel molecular mechanisms.

• Main Authors: María Gabriela Blanco (Author), María Soledad Vela Gurovic (Author), Gustavo Fabián Silbestri (Author), Andrés Garelli (Author), Sebastián Giunti (Author), Diego Rayes (Author), María José De Rosa (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nematode parasites cause substantial morbidity to billions of people and considerable losses in livestock and food crops. The repertoire of effective anthelmintic compounds for treating these parasitoses is very limited, as drug development has been delayed for decades. Moreover, resistance has beco...