A novel nonsense mutation in ARMC5 causes primary bilateral macronodular adrenocortical hyperplasia

• Main Authors: Wen-Tao He (Author), Xiong Wang (Author), Wen Song (Author), Xiao-Dong Song (Author), Yan-Jun Lu (Author), Yan-Kai Lv (Author), Ting He (Author), Xue-Feng Yu (Author), Shu-Hong Hu (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Primary bilateral macronodular adrenocortical hyperplasia (PBMAH) is a rare form of adrenal Cushing's syndrome. The slowly progressing expansion of bilateral adrenal tissues usually persists for dozens of years, leading to delayed onset with severe conditions due to chronic...