Structural Optimization of Platinum Drugs to Improve the Drug-Loading and Antitumor Efficacy of PLGA Nanoparticles

Structural Optimization of Platinum Drugs to Improve the Drug-Loading and Antitumor Efficacy of PLGA Nanoparticles

Currently, molecular dynamics simulation is being widely applied to predict drug-polymer interaction, and to optimize drug delivery systems. Our study describes a combination of in silico and in vitro approaches aimed at improvement in polymer-based nanoparticle design for cancer treatment. We appli...

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Main Authors: Maria B. Sokol (Author), Margarita V. Chirkina (Author), Nikita G. Yabbarov (Author), Mariia R. Mollaeva (Author), Tatyana A. Podrugina (Author), Anna S. Pavlova (Author), Viktor V. Temnov (Author), Rania M. Hathout (Author), Abdelkader A. Metwally (Author), Elena D. Nikolskaya (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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