Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial

• Main Authors: Shahin Lockman, MD (Author), Michael Hughes, ProfPhD (Author), Kate Powis, MD (Author), Gbolahan Ajibola, MB (Author), Kara Bennett, MS (Author), Sikhulile Moyo, MSc (Author), Erik van Widenfelt, BA (Author), Jean Leidner, MS (Author), Kenneth McIntosh, ProfMD (Author), Loeto Mazhani, MD (Author), Joseph Makhema, FRCP (Author), Max Essex, ProfPhD (Author), Roger Shapiro, DrMD (Author)
• Format: Book
• Published: Elsevier, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Co-trimoxazole prophylaxis reduces mortality among HIV-infected children, but efficacy in HIV-exposed but uninfected (HEU) children in a non-malarial, low-breastfeeding setting with a low risk of mother-to-child transmission of HIV is unclear. Methods: HEU children in Botswana w...