Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming

• Main Authors: Androniki Kretsovali (Author), Christiana Hadjimichael (Author), Nikolaos Charmpilas (Author)
• 格式: 图书
• 出版: Hindawi Limited, 2012-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Histone deacetylase inhibitors (HDACi) are small molecules that have important and pleiotropic effects on cell homeostasis. Under distinct developmental conditions, they can promote either self-renewal or differentiation of embryonic stem cells. In addition, they can promote directed differentiation...