A novel cryptic CBFB-MYH11 gene fusion present at birth leading to acute myeloid leukemia and allowing molecular monitoring for minimal residual disease

• Главные авторы: P.J. Poddighe (Автор), M.A. Veening (Автор), M.B. Mansur (Автор), A.H. Loonen (Автор), T.M. Westers (Автор), P.A. Merle (Автор), J.W. Wessels (Автор), V. de Haas (Автор), W.A. Kors (Автор), S.L. Bhola (Автор), M.J. Wondergem (Автор), A.M. Ford (Автор), G.J.L. Kaspers (Автор)
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• Опубликовано: Elsevier, 2018-03-01T00:00:00Z.
• Предметы: article
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Acute myeloid leukemia (AML) with the inv(16)/t(16;16) karyotype is associated with a favourable prognosis, showing longer periods of complete remission and high overall survival rates. Here we report a four year old girl, who presented with pallor, a history of viral infections and pancytopenia, an...