Genetic polymorphism of carcinogen metabolic enzymes in oral submucous fibrosis

• Main Authors: Sunu Ramachandran (Author), Anita Balan (Author), C Tinky Bose (Author), Prabha Balaram (Author), V Nityasri (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Biotransformation plays a crucial role in carcinogen activity. Genetic polymorphisms in xenobiotic-metabolizing enzymes crucial to a carcinogen and drug metabolism lead to variations in their activity. These enzymes increase cancer risk by an altered action on environmental carcinogens....