<i>N</i>-(2-Hydroxy)-propyl-3-trimethylammonium, <i>O</i>-Mysristoyl Chitosan Enhances the Solubility and Intestinal Permeability of Anticancer Curcumin

• Main Authors: Daniella S. Silva (Author), Danilo M. dos Santos (Author), Andreia Almeida (Author), Leonardo Marchiori (Author), Sérgio P. Campana-Filho (Author), Sidney J. L. Ribeiro (Author), Bruno Sarmento (Author)
• Format: Book
• Published: MDPI AG, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An amphiphilic derivative of chitosan containing quaternary ammonium and myristoyl groups, herein named as ammonium myristoyl chitosan (DMCat), was synthesized by reacting glycidyltrimethylammonium chloride (GTMAC) and myristoyl chitosan (DMCh). The success of the modification was confirmed using Fo...