Preparation and in vitro and in vivo evaluations of 10-hydroxycamptothecin liposomes modified with stearyl glycyrrhetinate

• Autori principali: Ting Zhou (Autore), Xin Tang (Autore), Wei Zhang (Autore), Jianfang Feng (Autore), Wei Wu (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

10-Hydroxycamptothecin (HCPT) liposomes surface modified with stearyl glycyrrhetinate (SG) were prepared by the film dispersion method. Characterization of the liposomes, including drug release in vitro, pharmacokinetics and tissue distribution, was done. HCPT in plasma and tissues was determined by...