SYN023, a novel humanized monoclonal antibody cocktail, for post-exposure prophylaxis of rabies.

• Main Authors: Tzu-Yuan Chao (Author), Shiqi Ren (Author), Enyun Shen (Author), Susan Moore (Author), Shou-Feng Zhang (Author), Li Chen (Author), Charles E Rupprecht (Author), Eric Tsao (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rabies is a neglected zoonotic disease that is preventable in humans by appropriate post-exposure prophylaxis (PEP). However, current PEP relies on polyclonal immune globulin products purified from pooled human (HRIG) or equine (ERIG) plasma that are either in chronic shortage or in association with...