Cinobufacini injection suppresses the proliferation of human osteosarcoma cells by inhibiting PIN1-YAP/TAZ signaling pathway

• Κύριοι συγγραφείς: Yuru Chen (Συγγραφέας), Yanyan Wang (Συγγραφέας), Yu Zhai (Συγγραφέας), Ye Yuan (Συγγραφέας), Junhong Wang (Συγγραφέας), Yajing Jin (Συγγραφέας), Lingling Dang (Συγγραφέας), Liming Song (Συγγραφέας), Changbao Chen (Συγγραφέας), Yu Wang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Cinobufacini injection (CI), an aqueous extract of Cutis Bufonis, is clinically used for cancer therapy in China, but its molecular mechanism for the treatment of osteosarcoma (OS) remains unclear. We constructed U2OS ectopic subcutaneous tumor model to verify the anti-OS effect of CI in vivo. Meanw...