Cinobufacini injection suppresses the proliferation of human osteosarcoma cells by inhibiting PIN1-YAP/TAZ signaling pathway

• मुख्य लेखकों: Yuru Chen (लेखक), Yanyan Wang (लेखक), Yu Zhai (लेखक), Ye Yuan (लेखक), Junhong Wang (लेखक), Yajing Jin (लेखक), Lingling Dang (लेखक), Liming Song (लेखक), Changbao Chen (लेखक), Yu Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cinobufacini injection (CI), an aqueous extract of Cutis Bufonis, is clinically used for cancer therapy in China, but its molecular mechanism for the treatment of osteosarcoma (OS) remains unclear. We constructed U2OS ectopic subcutaneous tumor model to verify the anti-OS effect of CI in vivo. Meanw...