The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation

• Main Authors: Valeriya Gushchina (Author), Nadja Kupper (Author), Michael Schwarzkopf (Author), Gitta Frisch (Author), Karina Piatek (Author), Cornelia Aigner (Author), Alexandra Michel (Author), Hemma Schueffl (Author), Luca Iamartino (Author), Taha Elajnaf (Author), Teresa Manhardt (Author), Andrea Vlasaty (Author), Petra Heffeter (Author), Marcella Bassetto (Author), Enikö Kállay (Author), Martin Schepelmann (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The prostaglandin E2 (PGE2) pathway is one of the main mediators of intestinal inflammation. As activation of the calcium-sensing receptor (CaSR) induces expression of inflammatory markers in the colon, we assessed the impact of the CaSR on the PGE2 pathway regulation in colon cancer c...