Glucocorticoid receptor expression in human bronchial epithelial cells: effects of smoking and COPD

• Main Authors: M. M. Verheggen (Author), P. W. C. Adriaansen-Soeting (Author), C. A. Berrevoets (Author), P. Th. W. van Hal (Author), A. O. Brinkmann (Author), H. C. Hoogsteden (Author), M. A. Versnel (Author)
• Format: Book
• Published: Hindawi Limited, 1998-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previously, we found that inflammatory mediators modulated the number and binding affinity of glucocorticoid receptors (GR) in human bronchial epithelial cell lines . In this study we investigated whether smoking and chronic obstructive pulmonary disease (COPD), both characterized by airway inflamma...