Design, synthesis and antitumor activity of coumarin, isoxazole, pyrazole, pyridine and pyrimidine compounds: 3β-hydroxypregn-5-ene-20-one derivatives

• Main Authors: Karam A. El-Sharkawy (Author), Hassan A. Alhazmi (Author), Asim Najmi (Author), Mohammed AlBratty (Author), Asaad Khalid (Author), Rym Hassani (Author), Sadique A. Javed (Author)
• Format: Book
• Published: Polskie Towarzystwo Farmaceutyczne, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In continuation of our reserach for synthesizing heterocyclic derivatives with a broad range of biological activities, the current research was performed to synthesize 3β-hydroxypregn-5-ene-20-one derivatives of coumarin, isoxazole, pyrazole, pyridine and pyrimidine and screen for antitumor activity...