Lipid droplets in granulosa cells are correlated with reduced pregnancy rates

• Auteurs principaux: Shira Raviv (Auteur), Shay Hantisteanu (Auteur), Shilhav Meisel Sharon (Auteur), Yuval Atzmon (Auteur), Mediea Michaeli (Auteur), Einat Shalom-Paz (Auteur)
• Format: Livre
• Publié: BMC, 2020-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background Lipids are an important source for energy production during oocyte maturation. The accumulation of intracellular lipids binds to proteins to form lipid droplets. This may lead to cellular lipotoxicity. The impact of lipotoxicity on cumulus and granulosa cells has been reported. T...