Asialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma

• Main Authors: Sandhya Pranatharthiharan (Author), Mitesh D. Patel (Author), Vinod C. Malshe (Author), Vaishali Pujari (Author), Ajit Gorakshakar (Author), Manisha Madkaikar (Author), Kanjaksha Ghosh (Author), Padma V. Devarajan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We report asialoglycoprotein receptor (ASGPR)-targeted doxorubicin hydrochloride (Dox) nanoparticles (NPs) for hepatocellular carcinoma (HCC). Polyethylene sebacate (PES)-Gantrez® AN 119 Dox NPs of average size 220 nm with PDI < 0.62 and ∼20% Dox loading were prepared by modified nanoprecipitatio...