The role of fibroblast growth factor signalling in Echinococcus multilocularis development and host-parasite interaction.

• Main Authors: Sabine Förster (Author), Uriel Koziol (Author), Tina Schäfer (Author), Raphael Duvoisin (Author), Katia Cailliau (Author), Mathieu Vanderstraete (Author), Colette Dissous (Author), Klaus Brehm (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Alveolar echinococcosis (AE) is a lethal zoonosis caused by the metacestode larva of the tapeworm Echinococcus multilocularis. The infection is characterized by tumour-like growth of the metacestode within the host liver, leading to extensive fibrosis and organ-failure. The molecular mech...