Epoxyeicosatrienoic Acid Analog EET-A Blunts Development of Lupus Nephritis in Mice

• Egile Nagusiak: Md. Abdul Hye Khan (Egilea), Anna Stavniichuk (Egilea), Mohammad Abdul Sattar (Egilea), John R. Falck (Egilea), John D. Imig (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disorder that causes life threatening renal disease and current therapies are limited with serious side-effects. CYP epoxygenase metabolites of arachidonic acid epoxyeicosatrienoic acids (EETs) demonstrate strong anti-inflammato...