Efflux Pumps of Gram-negative bacteria: What they do, how they do it, with what and how to deal with them

• Main Authors: Leonard eAmaral (Author), Ana eMartins (Author), Gabriella eSpengler (Author), Joseph eMolnar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This review discusses the relationship of the efflux pump system of Gram-negative bacteria to other antibiotic resistance mechanisms of the bacterium such as quorum sensing, biofilms, two component regulons, etc. The genetic responses of a Gram-negative to an antibiotic that render it immune to an a...