Intratracheal Administration of Chloroquine-Loaded Niosomes Minimize Systemic Drug Exposure

• Main Authors: Hesham A. Saafan (Author), Kamilia M. Ibrahim (Author), Yasmeena Thabet (Author), Sara M. Elbeltagy (Author), Rana A. Eissa (Author), Ashraf H. Ghaleb (Author), Fathy Ibrahim (Author), Mahmoud Elsabahy (Author), Noura G. Eissa (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary administration provides a useful alternative to oral and invasive routes of administration while enhancing and prolonging the accumulation of drugs into the lungs and reducing systemic drug exposure. In this study, chloroquine, as a model drug, was loaded into niosomes for potential pulmon...