Drug holiday of high-dose denosumab and recovery from osteoclast inhibition using immunohistochemical investigation of 7 patients with medication-related osteonecrosis of the jaw undergoing segmental mandibulectomy

Background/purpose: Denosumab is used to treat bone metastases from malignant tumors. Unlike bisphosphonates, denosumab is not deposited in the bone; thus, withdrawal for a relatively short period would help recovery from osteoclast suppression. This study investigated the relationship between drug...

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Main Authors: Shunsuke Sawada (Author), Yuki Sakamoto (Author), Mako Kirihigashi (Author), Yuka Kojima (Author)
Format: Book
Published: Elsevier, 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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