Probing the benzofuroquinolinium derivative as a potent antibacterial agent through the inhibition of FtsZ activity

• Main Authors: Ning Sun (Author), Li Ban (Author), Ming Li (Author), Zhiyuan Fang (Author), Xiaomei Li (Author), Wenxia Yao (Author), Jinghui Pan (Author), Yujing Lu (Author), Zhihua Liu (Author), Wing-Leung Wong (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A benzofuroquinolinium derivative that exhibits excellent cell division inhibitory effect was discovered through cell-based screening approach. This compound possesses potent antimicrobial activity against both Gram-positive and Gram-negative bacteria including the drug-resistant strains. In additio...