A phase I drug-drug interaction study to assess the effect of futibatinib on P‐gp and BCRP substrates and of P‐gp inhibition on the pharmacokinetics of futibatinib

A phase I drug-drug interaction study to assess the effect of futibatinib on P‐gp and BCRP substrates and of P‐gp inhibition on the pharmacokinetics of futibatinib

Abstract Futibatinib, an inhibitor of fibroblast growth factor receptor 1-4, is approved for the treatment of patients with advanced cholangiocarcinoma with FGFR2 fusions/rearrangements. In this phase I drug-drug interaction study, the effects of futibatinib on P‐glycoprotein (P‐gp) and breast cance...

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Main Authors: Amanda Long (Author), Ikuo Yamamiya (Author), Michelle Valentine (Author), Ziv Machnes (Author), Nanae Hangai (Author), Bailey Anderson (Author), Volker Wacheck (Author), Ling Gao (Author)
Format: Book
Published: Wiley, 2024-09-01T00:00:00Z.
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