Glycyrrhetinic Acid Protects Renal Tubular Cells against Oxidative Injury via Reciprocal Regulation of JNK-Connexin 43-Thioredoxin 1 Signaling

• Main Authors: Yao Zhou (Author), Leiping Gao (Author), Ping Xia (Author), Jing Zhao (Author), Wei Li (Author), Yufeng Zhou (Author), Qingxue Wei (Author), Qijing Wu (Author), Qi Wu (Author), Dongdong Sun (Author), Kun Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Objective: The incidence of chronic kidney disease (CKD) is steadily increasing. Although renal tubular epithelium injury is closely correlated with the prognosis of CKD, the underlying mechanism is not fully understood and therapeutic strategies are limited. The main bioactive compon...