Filaggrin and Atopic Dermatitis: Clinical and Pathogenetic Parallels and Therapeutic Possibilities

• Main Authors: Nikolay N. Murashkin (Author), Roman A. Ivanov (Author), Eduard T. Ambarchian (Author), Roman V. Epishev (Author), Alexander I. Materikin (Author), Leonid A. Opryatin (Author), Alena A. Savelova (Author)
• Format: Book
• Published: "Paediatrician" Publishers LLC, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atopic dermatitis (AtD) is multifactorial inflammatory skin disease, one of the aspects of its pathogenesis is epidermal barrier dysfunction. Early development of AtD is associated with filaggrin dysfunction. Filaggrin is a protein involved in aggregation of keratin filaments in the upper layers of...