Neuroprotective Effects of Phytochemicals against Aluminum Chloride-Induced Alzheimer's Disease through ApoE4/LRP1, Wnt3/β-Catenin/GSK3β, and TLR4/NLRP3 Pathways with Physical and Mental Activities in a Rat Model

• Main Authors: Ahmed Mohsen Elsaid Hamdan (Author), Fatimah Hussain J. Alharthi (Author), Ahmed Hadi Alanazi (Author), Soad Z. El-Emam (Author), Sameh S. Zaghlool (Author), Kamel Metwally (Author), Sana Abdulaziz Albalawi (Author), Yahia S. Abdu (Author), Reda El-Sayed Mansour (Author), Hoda A. Salem (Author), Zakaria Y. Abd Elmageed (Author), Karema Abu-Elfotuh (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Alzheimer's disease (AD) is a neurodegenerative disorder that is associated with abnormal cognition. AD is aided in its initiation and progression by hereditary and environmental factors. Aluminum (Al) is a neurotoxic agent that causes oxidative stress, which is linked to AD progres...