Hepatoprotective effect of Nobiletin against 5-fluorouracil induce hepatotoxicity

• Autori principali: Safa A. Yahya (Autore), Nada N. Al-Shawi (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2024-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

5-florouracil is a widely used anticancer/anti-metabolite drug used to treat solid tumor like colon cancer, head and neck, rectum, stomach, pancreas and breast cancer; but, it can cause hepatotoxicity by induction of apoptosis through activation of caspases enzymes and oxidative stress. Nobiletin is...