The Antibiotic-free pFAR4 Vector Paired with the Sleeping Beauty Transposon System Mediates Efficient Transgene Delivery in Human Cells

• Main Authors: Marie Pastor (Author), Sandra Johnen (Author), Nina Harmening (Author), Mickäel Quiviger (Author), Julie Pailloux (Author), Martina Kropp (Author), Peter Walter (Author), Zoltán Ivics (Author), Zsuzsanna Izsvák (Author), Gabriele Thumann (Author), Daniel Scherman (Author), Corinne Marie (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The anti-angiogenic and neurogenic pigment epithelium-derived factor (PEDF) demonstrated a potency to control choroidal neovascularization in age-related macular degeneration (AMD) patients. The goal of the present study was the development of an efficient and safe technique to integrate, ex vivo, t...